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Hunt, K. Malmberg et al. View at: Google Scholar E. Baker, C. Janaway, B. Philips et al. Sacks, S. Mayhew, and C. Merritt, Ed. Blood glucose levels can also be increased if too many calories are provided in the TPN from carbohydrates. The dextrose grams should be limited to grams per day to start. If levels are not monitored to ensure acceptable ranges, then blood glucose values can worsen. Hyperglycemia can also be related to infections patients on TPN may acquire while in the hospital.
Better patient outcomes are associated with improved blood glucose levels when patients are receiving TPN. The increase in mortality persisted even after accounting for patient age, nutritional status, sex, other medical conditions, high blood sugar prior to TPN, diabetes, C-reactive protein level, albumin level, hemoglobin levels or infections. If you or a loved one developed complications from a high blood sugar or hyperglycemia, we may be able to assist you.
Here at the Philadelphia Beasley medical malpractice law firm we have on staff physicians and nurses who have cared for patients on hyperalimentation or who had hyperglycemic episodes. Please feel free to contact one of our lawyers, doctors or nurses at for a strictly confidential and free consultation.
Methods We retrospectively collected the patient data from the electric medical record. Results General characteristics The general characteristics of the subjects are shown in Table 1. Table 1 General characteristics of the normoglycemia and hyperglycemia groups. Open in a separate window. Table 3 Stepwise multiple regression analysis. Discussion We demonstrated that dextrose delivery from TPN and mortality were significantly higher in the hyperglycemia group during the 1 st week of ICU care, which was similar to the results of previous studies [ 8 , 9 ].
References 1. Total parenteral nutrition in the surgical patient: a meta-analysis. Can J Surg. Intravenous glucose intake independently related to intensive care unit and hospital mortality: an argument for glucose toxicity in critically ill patients. Clin Endocrinol Oxf ; 64 — Clin Nutr. Hyperglycemia is associated with adverse outcomes in patients receiving total parenteral nutrition. Diabetes Care. Effects of hyperglycemia and insulin therapy on outcome in a hyperglycemic septic model of critical illness.
J Trauma. Hyperglycemia associated with high, continuous infusion rates of total parenteral nutrition dextrose. Nutr Clin Pract. Hyperglycemia correlates with outcomes in patients receiving total parenteral nutrition.
Am J Med Sci. Hyperglycemia during total parenteral nutrition: an important marker of poor outcome and mortality in hospitalized patients. Intensive insulin therapy in the critically ill patients. N Engl J Med. Intensive insulin therapy in the medical ICU. J Clin Endocrinol Metab. Parenteral nutrition implementation and management. In: Merrit R, editor. The A. Nutrition Support Practice Manual. Parenteral nutrition in patients with diabetes mellitus: theoretical and practical considerations.
Metabolic and monetary costs of avoidable parenteral nutrition use. A nutrition support team led by general surgeons decreases inappropriate use of total parenteral nutrition on a surgical service.
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